DMP1 antibody (AA 561-760)

Catalog No. ABIN7266560

Product Details anti-DMP1 Antibody

Target: DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

Binding Specificity: AA 561-760

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: DMTF1 Rabbit pAb

Sequence: VTVQCHTPRV IIQTVATEDI TSSISQAELT VDSDIQSSDF PEPPDALEAD TFPDEIHHPK MTVEPSFNDA HVSKFSDQNS TELMNSVMVR TEEEISDTDL KQEESPSDLA SAYVTEGLES PTIEEQVDQT IDDETILIVP SPHGFIQASD VIDTESVLPL TTLTDPILQH HQEESNIIGS SLGSPVSEDS KDVEDLVNCH

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 561-760 of human DMTF1 (NP_066968.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DMP1

Target: DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

Alternative Name: DMTF1 (DMTF1 Products)

Synonyms: DMP1 antibody, DMTF antibody, hDMP1 antibody, Dimp antibody, Dmp1 antibody, DMTF1 antibody, zgc:92448 antibody, cyclin D binding myb like transcription factor 1 antibody, cyclin D binding myb-like transcription factor 1 antibody, DMTF1 antibody, Dmtf1 antibody, dmtf1 antibody

Background: This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40 % of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene.,DMTF1,DMP1,DMTF,MRUL,hDMP1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cyclins,DMTF1

Gene ID: 9988

UniProt: Q9Y222