DIAPH1 antibody (AA 1149-1263)

Catalog No. ABIN7266750

The Rabbit Polyclonal anti-DIAPH1 antibody (ABIN7266750) specifically detects DIAPH1 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for DIAPH1 antibody (AA 1149-1263) (ABIN7266750)

Target: DIAPH1 (Diaphanous Homolog 1 (DIAPH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIAPH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Grade: KO Validated

Product Details anti-DIAPH1 Antibody

Binding Specificity: AA 1149-1263

Purpose: [KO Validated] DIAPH1 Rabbit pAb

Sequence: TEEKMRRAKL AKEKAEKERL EKQQKREQLI DMNAEGDETG VMDSLLEALQ SGAAFRRKRG PRQANRKAGC AVTSLLASEL TKDDAMAAVP AKVSKNSETF PTILEEAKEL VGRAS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1149-1263 of human DIAPH1 (NP_001073280.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DIAPH1

Target: DIAPH1 (Diaphanous Homolog 1 (DIAPH1))

Alternative Name: DIAPH1

Background: This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,DIAPH1,DFNA1,DIA1,DRF1,LFHL1,SCBMS,hDIA1,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microfilaments,Microtubules,Actins,TGF-b-Smad Signaling Pathway,DIAPH1

Molecular Weight: 138kDa/140kDa/141kDa

Gene ID: 1729

UniProt: O60610

Pathways: Sensory Perception of Sound