Endoglin antibody

Catalog No. ABIN7266938

The Rabbit Monoclonal anti-Endoglin antibody has been validated for WB and IHC. It is suitable to detect Endoglin in samples from Human.

Quick Overview for Endoglin antibody (ABIN7266938)

Target: Endoglin (ENG)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Endoglin Antibody

Purpose: CD105/Endoglin Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human CD105/Endoglin

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: ENG

Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],END,HHT1,ORW1,CD105,ENG,endoglin,Cancer,Cardiovascular,Cardiovascular Markers,Cardiovascular Markers_Endothelial Cells,CDs,Endothelial Progenitors,Immunology & Inflammation,Mesenchymal Stem Cells,Stem Cells,Tumor biomarkers,ENG

Molecular Weight: 90kDa

Gene ID: 2022

UniProt: P17813