Endoglin antibody (AA 26-306)

Catalog No. ABIN7266939

This anti-Endoglin antibody is a Rabbit Polyclonal antibody detecting Endoglin in WB. Suitable for Human.

Quick Overview for Endoglin antibody (AA 26-306) (ABIN7266939)

Target: Endoglin (ENG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Endoglin Antibody

Binding Specificity: AA 26-306

Purpose: CD105/Endoglin Rabbit pAb

Sequence: ETVHCDLQPV GPERGEVTYT TSQVSKGCVA QAPNAILEVH VLFLEFPTGP SQLELTLQAS KQNGTWPREV LLVLSVNSSV FLHLQALGIP LHLAYNSSLV TFQEPPGVNT TELPSFPKTQ ILEWAAERGP ITSAAELNDP QSILLRLGQA QGSLSFCMLE ASQDMGRTLE WRPRTPALVR GCHLEGVAGH KEAHILRVLP GHSAGPRTVT VKVELSCAPG DLDAVLILQG PPYVSWLIDA NHNMQIWTTG EYSFKIFPEK NIRGFKLPDT PQGLLGEARM L

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-306 of human CD105/Endoglin (NP_001108225.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: ENG

Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,END,HHT1,ORW1,CD105,ENG,endoglin,Cancer,Tumor biomarkers,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Mesenchymal Stem Cells,Cardiovascular,Cardiovascular Markers,Endothelial Cells,ENG

Molecular Weight: 67kDa/70kDa

Gene ID: 2022

UniProt: P17813