GRIK2 antibody

Catalog No. ABIN7267415

The Rabbit Monoclonal anti-GRIK2 antibody has been validated for WB and IHC. It is suitable to detect GRIK2 in samples from Human.

Quick Overview for GRIK2 antibody (ABIN7267415)

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GRIK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GRIK2 Antibody

Purpose: GRIK2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human GRIK2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GRIK2

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Alternative Name: GRIK2

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008],EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6,Apoptosis,Cell Biology & Developmental Biology,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Neuroscience,Signal Transduction,GRIK2

Molecular Weight: 103kDa

Gene ID: 2898

UniProt: Q13002

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity