GRIK2 antibody (AA 203-500)

Catalog No. ABIN7153973

Product Details anti-GRIK2 Antibody

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Binding Specificity: AA 203-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIK2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Glutamate receptor ionotropic, kainate 2 protein (203-500AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GRIK2

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Alternative Name: GRIK2 (GRIK2 Products)

Synonyms: GRIK5 antibody, eaa4 antibody, glr6 antibody, gluk6 antibody, glur6 antibody, grik2 antibody, mrt6 antibody, GluR6 antibody, grik2-A antibody, EAA4 antibody, GLR6 antibody, GLUK6 antibody, GLUR6 antibody, GluK2 antibody, MRT6 antibody, AW124492 antibody, Glur-6 antibody, Glur6 antibody, Glurbeta2 antibody, GRIK2 antibody, glutamate ionotropic receptor kainate type subunit 2 antibody, glutamate receptor, ionotropic, kainate 2 L homeolog antibody, glutamate receptor, ionotropic, kainate 2 antibody, glutamate receptor, ionotropic, kainate 2 (beta 2) antibody, GRIK2 antibody, grik2.L antibody, grik2 antibody, Grik2 antibody

Background:

Background: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:28180184). May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity).

Aliases: bA487F5.1 antibody, EAA4 antibody, Excitatory amino acid receptor 4 antibody, GLR 6 antibody, GLR6 antibody, GluK2 antibody, GLUK6 antibody, GLUR 6 antibody, GluR-6 antibody, GluR6 antibody, Glutamate receptor 6 antibody, Glutamate receptor antibody, glutamate receptor form A antibody, glutamate receptor form B antibody, glutamate receptor form C antibody, glutamate receptor form D antibody, glutamate receptor form E antibody, Glutamate receptor ionotropic kainate 2 antibody, GRIK 2 antibody, GRIK2 antibody, GRIK2 protein antibody, GRIK2_HUMAN antibody, ionotropic kainate 2 antibody, MRT6 antibody

UniProt: Q13002

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity