GRIK2 antibody (AA 45-226)

Catalog No. ABIN5611208

This Mouse Monoclonal antibody specifically detects GRIK2 in ELISA. It exhibits reactivity toward Human.

Quick Overview for GRIK2 antibody (AA 45-226) (ABIN5611208)

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRIK2 antibody is un-conjugated

Application: ELISA

Clone: 8A1F11

Product Details anti-GRIK2 Antibody

Binding Specificity: AA 45-226

Purpose: GRIK2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human GRIK2 (AA: 45-226) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for GRIK2

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Alternative Name: GRIK2

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Molecular Weight: 102.5 kDa

Gene ID: 2898

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity