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HIRA antibody

HIRA Reactivity: Human WB Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7267656
$785.90
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 10 to 11 Business Days
  • Target See all HIRA Antibodies
    HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
    Reactivity
    • 47
    • 33
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 53
    • 12
    Rabbit
    Clonality
    • 54
    • 11
    Monoclonal
    Conjugate
    • 32
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIRA antibody is un-conjugated
    Application
    • 37
    • 24
    • 13
    • 13
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    HIRA Rabbit mAb
    Cross-Reactivity
    Human
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human HIRA
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
    Alternative Name
    HIRA (HIRA Products)
    Synonyms
    HIRA antibody, wu:fb97b07 antibody, wu:fi43b08 antibody, si:ch211-188g24.3 antibody, AA138857 antibody, D16Ertd95e antibody, N28177 antibody, Tuple1 antibody, DGCR1 antibody, TUP1 antibody, TUPLE1 antibody, dgcr1 antibody, hira-A antibody, tup1 antibody, tuple1 antibody, homolog of histone chaperone HIRA antibody, histone cell cycle regulator antibody, histone cell cycle regulator a antibody, protein HIRA antibody, HIR histone cell cycle regulation defective homolog A (S. cerevisiae) antibody, HIRA antibody, histone cell cycle regulator S homeolog antibody, histone chaperone HIRA-like protein antibody, Tuple1/HirA antibody, HIRA antibody, hira antibody, LOC100052845 antibody, LOC100352472 antibody, LOC100407742 antibody, LOC100450459 antibody, LOC100467668 antibody, LOC100581135 antibody, LOC486424 antibody, Hira antibody, LOC732736 antibody, hira.S antibody
    Background
    This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008],DGCR1, TUP1, TUPLE1,Cell Biology & Developmental Biology,Chromatin Remodeling,Epigenetics & Nuclear Signaling,Germline Stem Cells,Stem Cells,HIRA
    Molecular Weight
    112kDa
    Gene ID
    7290
    UniProt
    P54198
    Pathways
    Chromatin Binding
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