IFNAR1 antibody (AA 470-557)

Catalog No. ABIN7267947

This anti-IFNAR1 antibody is a Rabbit Polyclonal antibody detecting IFNAR1 in WB, IHC and IF. Suitable for Human.

Quick Overview for IFNAR1 antibody (AA 470-557) (ABIN7267947)

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNAR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IFNAR1 Antibody

Binding Specificity: AA 470-557

Purpose: IFNAR1 Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 470-557 of human IFNAR1 (NP_000620.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IFNAR1

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Alternative Name: IFNAR1

Background: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.,IFNAR1,AVP,IFN-alpha-REC,IFNAR,IFNBR,IFRC,Cancer,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,Cytokines_Interferons,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Signal Transduction,Tumor immunology,IFNAR1

Molecular Weight: 49kDa/56kDa/63kDa

Gene ID: 3454

UniProt: P17181

Pathways: JAK-STAT Signaling, Hepatitis C