IQGAP1 antibody

Catalog No. ABIN7268019

The Rabbit Monoclonal anti-IQGAP1 antibody (ABIN7268019) specifically detects IQGAP1 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for IQGAP1 antibody (ABIN7268019)

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IQGAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IQGAP1 Antibody

Purpose: IQGAP1 Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human IQGAP1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IQGAP1

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Alternative Name: IQGAP1

Background: This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],HUMORFA01, SAR1, p195,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Endocrine & Metabolism,G protein signaling,G protein signaling_Small G proteins,Signal Transduction,IQGAP1

Molecular Weight: 195kDa

Gene ID: 8826

UniProt: P46940

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2