IQGAP1 antibody (AA 500-750)

Catalog No. ABIN7268020

This Rabbit Polyclonal antibody specifically detects IQGAP1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for IQGAP1 antibody (AA 500-750) (ABIN7268020)

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQGAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IQGAP1 Antibody

Binding Specificity: AA 500-750

Purpose: IQGAP1 Rabbit pAb

Sequence: ELMKLKAQAH AENNEFITWN DIQACVDHVN LVVQEEHERI LAIGLINEAL DEGDAQKTLQ ALQIPAAKLE GVLAEVAQHY QDTLIRAKRE KAQEIQDESA VLWLDEIQGG IWQSNKDTQE AQKFALGIFA INEAVESGDV GKTLSALRSP DVGLYGVIPE CGETYHSDLA EAKKKKLAVG DNNSKWVKHW VKGGYYYYHN LETQEGGWDE PPNFVQNSMQ LSREEIQSSI SGVTAAYNRE QLWLANEGLI T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human IQGAP1 (NP_003861.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IQGAP1

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Alternative Name: IQGAP1

Background: This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.,IQGAP1,HUMORFA01,SAR1,p195,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Endocrine & Metabolism,IQGAP1

Molecular Weight: 189kDa

Gene ID: 8826

UniProt: P46940

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2