IQGAP1 antibody (AA 1451-1550)

Catalog No. ABIN737796

Product Details anti-IQGAP1 Antibody

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Binding Specificity: AA 1451-1550

Reactivity: Human, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQGAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rabbit, Rat

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IQGAP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IQGAP1 antibody (ABIN737796)

Fang, Zhang, Liu, Li, Zhou, Song, Zhao, Feng, Zhang, Li, Wen: "PAX6 downregulates miR-124 expression to promote cell migration during embryonic stem cell differentiation." in: Stem cells and development, Vol. 23, Issue 19, pp. 2297-310, (2014) (PubMed).

Target Details for IQGAP1

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Alternative Name: IQGAP1 (IQGAP1 Products)

Synonyms: HUMORFA01 antibody, SAR1 antibody, p195 antibody, AA682088 antibody, D7Ertd237e antibody, D7Ertd257e antibody, mKIAA0051 antibody, IQ motif containing GTPase activating protein 1 antibody, IQGAP1 antibody, Iqgap1 antibody

Background:

Synonyms: SAR1, p195, HUMORFA1, Ras GTPase-activating-like protein IQGAP1, IQGAP1, KIAA51

Background: Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.

Gene ID: 8826

UniProt: P46940

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2