NLRP6 antibody (AA 100-200)

Catalog No. ABIN7268941

This Rabbit Polyclonal antibody specifically detects NLRP6 in WB. It exhibits reactivity toward Human.

Quick Overview for NLRP6 antibody (AA 100-200) (ABIN7268941)

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NLRP6 Antibody

Binding Specificity: AA 100-200

Purpose: NLRP6 Rabbit pAb

Sequence: RRLQRLGLGS GTLLSVSEYK KKYREHVLQL HARVKERNAR SVKITKRFTK LLIAPESAAP EEAMGPAEEP EPGRARRSDT HTFNRLFRRD EEGRRPLTVV L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NLRP6 (NP_001263629.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NLRP6

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Alternative Name: NLRP6

Background: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.,NLRP6,AVR,CLR11.4,NALP6,NAVR,NAVR/AVR,PAN3,PYPAF5,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,NLRP6

Molecular Weight: 99kDa

Gene ID: 171389

UniProt: P59044

Pathways: Inflammasome