NLRP6 antibody (AA 168-197)

Catalog No. ABIN3032023

This Rabbit Polyclonal antibody specifically detects NLRP6 in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for NLRP6 antibody (AA 168-197) (ABIN3032023)

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP6 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-NLRP6 Antibody

Binding Specificity: AA 168-197

Purpose: NLRP6 Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 168-197 from the human protein was used as the immunogen for this NLRP6 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NLRP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NLRP6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NLRP6

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Alternative Name: NLRP6

Background: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1, also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.

UniProt: P59044

Pathways: Inflammasome