NCOA1 antibody

Catalog No. ABIN7269005

The Rabbit Monoclonal anti-NCOA1 antibody has been validated for WB and IP. It is suitable to detect NCOA1 in samples from Human.

Quick Overview for NCOA1 antibody (ABIN7269005)

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NCOA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-NCOA1 Antibody

Purpose: KAT13A / SRC1 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human KAT13A / SRC1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NCOA1

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Alternative Name: NCOA1

Background: The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74,Cancer,Endocrine & Metabolism,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Acetylation,Epigenetics & Nuclear Signaling,Lipid Metabolism,Nuclear Receptor Signaling,Nuclear Receptor Signaling_Nuclear hormone receptors,Signal Transduction,NCOA1

Molecular Weight: 157kDa

Gene ID: 8648

UniProt: Q15788

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha