NUMB antibody

Catalog No. ABIN7269073

This Rabbit Monoclonal antibody specifically detects NUMB in WB and IP. It exhibits reactivity toward Human.

Quick Overview for NUMB antibody (ABIN7269073)

Target: NUMB (Numb Homolog (NUMB))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NUMB antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-NUMB Antibody

Purpose: NUMB Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human NUMB

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NUMB

Target: NUMB (Numb Homolog (NUMB))

Alternative Name: NUMB

Background: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],C14orf41, S171, c14_5527,Cell Biology & Developmental Biology,Neuroscience,Notch Signaling Pathway,Signal Transduction,Stem Cells,NUMB

Molecular Weight: 71kDa

Gene ID: 8650

UniProt: P49757

Pathways: Cell-Cell Junction Organization