OTX2 antibody

Catalog No. ABIN7269116

The Rabbit Monoclonal anti-OTX2 antibody has been validated for WB. It is suitable to detect OTX2 in samples from Human.

Quick Overview for OTX2 antibody (ABIN7269116)

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This OTX2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OTX2 Antibody

Purpose: OTX2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human OTX2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OTX2

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Alternative Name: OTX2

Background: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012],CPHD6, MCOPS5,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Neuroscience,Stem Cells,Transcription Factors,OTX2

Molecular Weight: 32kDa

Gene ID: 5015

UniProt: P32243

Pathways: Dopaminergic Neurogenesis