PIM3 antibody (AA 247-326)

Catalog No. ABIN7269376

This Rabbit Polyclonal antibody specifically detects PIM3 in WB. It exhibits reactivity toward Human.

Quick Overview for PIM3 antibody (AA 247-326) (ABIN7269376)

Target: PIM3 (Pim-3 Oncogene (PIM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIM3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIM3 Antibody

Binding Specificity: AA 247-326

Purpose: PIM3 Rabbit pAb

Sequence: QDEEILRGRL LFRRRVSPEC QQLIRWCLSL RPSERPSLDQ IAAHPWMLGA DGGVPESCDL RLCTLDPDDV ASTTSSSESL

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 247-326 of human PIM3 (NP_001001852.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PIM3

Target: PIM3 (Pim-3 Oncogene (PIM3))

Alternative Name: PIM3

Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.,PIM3,pim-3,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PIM3

Molecular Weight: 37kDa

Gene ID: 415116

UniProt: Q86V86

Pathways: Negative Regulation of Hormone Secretion