ROR2 antibody (AA 300-400)

Catalog No. ABIN7269889

This Rabbit Polyclonal antibody specifically detects ROR2 in WB. It exhibits reactivity toward Human.

Quick Overview for ROR2 antibody (AA 300-400) (ABIN7269889)

Target: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROR2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ROR2 Antibody

Binding Specificity: AA 300-400

Purpose: ROR2 Rabbit pAb

Sequence: CMRIGIPAER LGRYHQCYNG SGMDYRGTAS TTKSGHQCQP WALQHPHSHH LSSTDFPELG GGHAYCRNPG GQMEGPWCFT QNKNVRMELC DVPSCSPRDS S

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-400 of human ROR2 (NP_004551.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ROR2

Target: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Alternative Name: ROR2

Background: The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.,ROR2,BDB,BDB1,NTRKR2,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Stem Cells,Mesenchymal Stem Cells,ROR2

Molecular Weight: 104kDa

Gene ID: 4920

UniProt: Q01974

Pathways: RTK Signaling, WNT Signaling