RUNX1 antibody

Catalog No. ABIN7270116

The Rabbit Monoclonal anti-RUNX1 antibody (ABIN7270116) specifically detects RUNX1 in WB. The antibody is reactive with Human samples.

Quick Overview for RUNX1 antibody (ABIN7270116)

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RUNX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RUNX1 Antibody

Purpose: RUNX1 Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human RUNX1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Alternative Name: RUNX1

Background: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Hematopoietic Progenitors,Hippo Signaling Pathway,Neuroscience,Protein phosphorylation,Stem Cells,Transcription Factors,RUNX1

Molecular Weight: 51kDa

Gene ID: 861

UniProt: Q01196, Q13761, Q13950