SMPD4 antibody (AA 600-800)

Catalog No. ABIN7270531

This Rabbit Polyclonal antibody specifically detects SMPD4 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for SMPD4 antibody (AA 600-800) (ABIN7270531)

Target: SMPD4 (Sphingomyelin Phosphodiesterase 4 (SMPD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMPD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-SMPD4 Antibody

Binding Specificity: AA 600-800

Purpose: SMPD4 Rabbit pAb

Sequence: ITQAKHTAKS ISDQCAESPA GHSFLSWLGF SSMDTNGSYT ANDLDEMGQD SVRKTDEYLE KALEYLRQIF RLSEAQLRQF TLALGTTQDE NGKKQLPDCI VGEDGLILTP LGRYQIINGL RRFEIEYQGD PELQPIRSYE IASLVRTLFR LSSAINHRFA GQMAALCSRD DFLGSFCRYH LTEPGLASRH LLSPVGRRQV A

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-800 of human SMPD4 (NP_060421.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMPD4

Target: SMPD4 (Sphingomyelin Phosphodiesterase 4 (SMPD4))

Alternative Name: SMPD4

Background: The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.,SMPD4,NET13,NSMASE-3,NSMASE3,Neuroscience,SMPD4

Molecular Weight: 44kDa, 56-69kDa, 83-98kDa

Gene ID: 55627

UniProt: Q9NXE4