SMPD4 antibody

Catalog No. ABIN7467837

This Rabbit Polyclonal antibody specifically detects SMPD4 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for SMPD4 antibody (ABIN7467837)

Target: SMPD4 (Sphingomyelin Phosphodiesterase 4 (SMPD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMPD4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SMPD4 Antibody

Cross-Reactivity: Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SMPD4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.78 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SMPD4

Target: SMPD4 (Sphingomyelin Phosphodiesterase 4 (SMPD4))

Alternative Name: sphingomyelin phosphodiesterase 4

Background: Sphingomyelin phosphodiesterase 4 , NET13 , NSMASE-3 , NSMASE3 , SKNY,The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network. [provided by RefSeq, Mar 2017]

Molecular Weight: 93 kDa

Gene ID: 55627

UniProt: Q9NXE4