Syntaxin 17 antibody (AA 1-130)

Catalog No. ABIN7270682

Product Details anti-Syntaxin 17 Antibody

Target: Syntaxin 17 (STX17)

Binding Specificity: AA 1-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 17 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: STX17 Rabbit pAb

Sequence: MSEDEEKVKL RRLEPAIQKF IKIVIPTDLE RLRKHQINIE KYQRCRIWDK LHEEHINAGR TVQQLRSNIR EIEKLCLKVR KDDLVLLKRM IDPVKEEASA ATAEFLQLHL ESVEELKKQF NDEETLLQPP

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human STX17 (NP_060389.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Syntaxin 17

Target: Syntaxin 17 (STX17)

Alternative Name: STX17 (STX17 Products)

Synonyms: CG7452 antibody, Dm Syx17 antibody, DmSyx17 antibody, Dmel\\CG7452 antibody, Syx antibody, GB16255 antibody, syntaxin-17 antibody, zgc:101617 antibody, NV17661 antibody, 4833418L03Rik antibody, 6330411F21Rik antibody, 9030425C21Rik antibody, AW048351 antibody, Syntaxin 17 antibody, syntaxin-17 antibody, syntaxin 17 antibody, Syx17 antibody, LOC410719 antibody, STX17 antibody, stx17 antibody, Stx17 antibody

Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi.,STX17,Signal Transduction,STX17

Gene ID: 55014

UniProt: P56962

Pathways: Synaptic Vesicle Exocytosis