T-Box 5 antibody (AA 1-70)

Catalog No. ABIN7270701

This anti-T-Box 5 antibody is a Rabbit Polyclonal antibody detecting T-Box 5 in WB. Suitable for Human.

Quick Overview for T-Box 5 antibody (AA 1-70) (ABIN7270701)

Target: T-Box 5 (TBX5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-T-Box 5 Antibody

Binding Specificity: AA 1-70

Purpose: TBX5 Rabbit pAb

Sequence: MADADEGFGL AHTPLEPDAK DLPCDSKPES ALGAPSKSPS SPQAAFTQQG MEGIKVFLHE RELWLKFHEV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human TBX5 (NP_852259.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for T-Box 5

Target: T-Box 5 (TBX5)

Alternative Name: TBX5

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.,TBX5,HOS,T-box 5,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,Cardiovascular,Heart,Cardiogenesis,TBX5

Molecular Weight: 39kDa/52kDa/57kDa

Gene ID: 6910

UniProt: Q99593