TBK1 antibody (pSer172)

Catalog No. ABIN7270721

The Rabbit Monoclonal anti-TBK1 antibody has been validated for WB. It is suitable to detect TBK1 in samples from Human.

Quick Overview for TBK1 antibody (pSer172) (ABIN7270721)

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TBK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBK1 Antibody

Binding Specificity: pSer172

Purpose: Phospho-TBK1/NAK-S172 Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding S172 of human TBK1/NAK

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TBK1

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Alternative Name: TBK1

Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],FTDALS4, NAK, T2K,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,NF-kB Signaling Pathway,PI3K-Akt Signaling Pathway,PI3K-Akt Signaling Pathway_Kinase of Akt,Protein phosphorylation,Signal Transduction,Toll-like Receptor Signaling Pathway,TBK1

Molecular Weight: 84kDa

Gene ID: 29110

UniProt: Q9UHD2

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome