TBL1X antibody (AA 100-200)

Catalog No. ABIN7270901

The Rabbit Polyclonal anti-TBL1X antibody is suitable to detect TBL1X in samples from Human. It has been validated for WB.

Quick Overview for TBL1X antibody (AA 100-200) (ABIN7270901)

Target: TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBL1X antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBL1X Antibody

Binding Specificity: AA 100-200

Purpose: TBL1X Rabbit pAb

Sequence: LISILQKGLQ YVEAEISINE DGTVFDGRPI ESLSLIDAVM PDVVQTRQQA FREKLAQQQA SAAAAAAAAT AAATAATTTS AGVSHQNPSK NREATVNGEE N

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TBL1X (NP_005638.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TBL1X

Target: TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))

Alternative Name: TBL1X

Background: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.,TBL1X,EBI,SMAP55,TBL1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Endocrine & Metabolism,Lipid Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Neuroscience,TBL1X

Molecular Weight: 57kDa/62kDa

Gene ID: 6907

UniProt: O60907

Pathways: Sensory Perception of Sound, Regulation of Lipid Metabolism by PPARalpha