WASF1 antibody (C-Term)

Catalog No. ABIN7271345

The Rabbit Polyclonal anti-WASF1 antibody has been validated for WB. It is suitable to detect WASF1 in samples from Human.

Quick Overview for WASF1 antibody (C-Term) (ABIN7271345)

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WASF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WASF1 Antibody

Binding Specificity: C-Term

Purpose: WASF1 Rabbit pAb

Sequence: VARAAPVCET VPVHPLPQGE VQGLPPPPPP PPLPPPGIRP SSPVTVTALA HPPSGLHPTP STAPGPHVPL MPPSPPSQVI PASEPKRHPS TLPVISDARS VLLEAIRKGI QLRKVEEQRE QEAKHERIEN DVATILSRRI AVEYSDSEDD SEFDEVDWLE

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human WASF1 (NP_001020107.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WASF1

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Alternative Name: WASF1

Background: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.,WASF1,SCAR1,WAVE,WAVE1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Extracellular Matrix,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,WASF1

Molecular Weight: 61kDa

Gene ID: 8936

UniProt: Q92558

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization