WISP3 antibody (AA 42-260)

Catalog No. ABIN7271384

The Rabbit Polyclonal anti-WISP3 antibody is suitable to detect WISP3 in samples from Human. It has been validated for WB.

Quick Overview for WISP3 antibody (AA 42-260) (ABIN7271384)

Target: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WISP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WISP3 Antibody

Binding Specificity: AA 42-260

Purpose: WISP3 Rabbit pAb

Sequence: TGPLDTTPEG RPGEVSDAPQ RKQFCHWPCK CPQQKPRCPP GVSLVRDGCG CCKICAKQPG EICNEADLCD PHKGLYCDYS VDRPRYETGV CAYLVAVGCE FNQVHYHNGQ VFQPNPLFSC LCVSGAIGCT PLFIPKLAGS HCSGAKGGKK SDQSNCSLEP LLQQLSTSYK TMPAYRNLPL IWKKKCLVQA TKWTPCSRTC GMGISNRVTN ENSNCEMRK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 42-260 of human WISP3 (NP_937882.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WISP3

Target: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Alternative Name: WISP3

Background: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.,WISP3,CCN6,LIBC,PPAC,PPD,WISP-3,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Stem Cells,Mesenchymal Stem Cells,WISP3

Molecular Weight: 39kDa/41kDa

Gene ID: 8838

UniProt: O95389

Pathways: WNT Signaling, Growth Factor Binding