Endoglin antibody

Catalog No. ABIN7271837

The Mouse Monoclonal anti-Endoglin antibody has been validated for FACS. It is suitable to detect Endoglin in samples from Human.

Quick Overview for Endoglin antibody (ABIN7271837)

Target: Endoglin (ENG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: SN6h

Product Details anti-Endoglin Antibody

Purpose: CD105 Unconjugated Antibody

Characteristics: The clone SN6h, a mouse monoclonal antibody selectively binds to a ~95 kDa type I transmembrane homodimer glycoprotein known as CD105. It is also encoded by END (Endoglin) and belongs to the TGF-β type III receptor family. CD105 mostly expressed on vascular endothelial cells, placental syncytiotrophoblasts, mesenchymal stem cells, erythroid precursors, activated macrophages, pre-B cells, and some tumor cells and cell lines including U937 cells. CD105 works as an important regulatory component of the TGF-β receptor system. CD105 expression is increased on activated endothelium tissues undergoing angiogenesis and also in cases of wound healing or dermal inflammation. CD105 may also be involved in the solid tumor metastasis, in regulation of cytoskeletal cellular organization as well as migration.

Purification: Purified

Purity: >95 %

Immunogen: EDG (CD105) isolated from acute lymphoblastic leukemia cells

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105

Gene ID: 2022

UniProt: P17813