CD14 antibody (AA 25-148)

Catalog No. ABIN7271857

This Mouse Monoclonal antibody specifically detects CD14 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD14 antibody (AA 25-148) (ABIN7271857)

Target: CD14

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: C-2386

Product Details anti-CD14 Antibody

Binding Specificity: AA 25-148

Purpose: CD14 Unconjugated Antibody

Characteristics: The clone C-2386, a mouse monoclonal antibody reacts with a human 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain cell surface antigen known as CD14. The CD14 expression is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. C-2386 binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes.    

Purification: Purified

Purity: >95 %

Immunogen: Recombinant fragment of human CD14 protein (around aa 25-148)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD14

Target: CD14

Alternative Name: CD14

Gene ID: 929

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades