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Bcl-2 antibody (AA 41-54)

The Mouse Monoclonal anti-Bcl-2 antibody (Clone 1E2) (ABIN7272015) specifically detects Bcl-2 in FACS. The antibody is reactive with Human samples.

Catalog No. ABIN7272015

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$157.63

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Quick Overview for Bcl-2 antibody (AA 41-54) (ABIN7272015)

Target

See all Bcl-2 (BCL2) Antibodies

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity

Human

Host

Mouse

Clonality

Monoclonal

Conjugate

This Bcl-2 antibody is un-conjugated

Application

Flow Cytometry (FACS)

Grade

GMP Grade

Clone

1E2

Discover our top product BCL2 Primary Antibody

Binding Specificity
54

38

27

24

22

21

16

16

16

12

11

11

7

7

7

6

6

6

5

4

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 41-54

Purpose

BCL-2 Unconjugated Antibody

Characteristics

The clone 100, a mouse monoclonal antibody, recognizes a 239 amino acid ~25 kDa human apoptosis regulator oncoprotein known as Bcl-2. It is an intracellular, integral membrane protein containing up to 4 Bcl-2 homology (BH) motifs which are found primarily in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membrane. Bcl-2 is a conserved anti-apoptotic protein and plays important roles in the management of normal immunity. Nonrandom translocations with breakpoint at band q21 on chromosome 18 may cause bcl-2 gene deregulation and contribute to neoplastic transformation in human lymphomas.

Purification

Purified

Purity

>95 %

Immunogen

Human BCL-2 synthetic peptide aa. 41-54

Isotype

IgG1, kappa
anti-B-Cell CLL/lymphoma 2 (BCL2) (N-Term) antibody
BCL2 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
BCL2 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 101-160) antibody
BCL2 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Chicken, Bacteria WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 75-110) antibody
BCL2 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB04684 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
BCL2 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal D1 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
BCL2 Reactivity: Human WB, FACS, IP, IHC (p), ICC, IHC (fro) Host: Mouse Monoclonal Bcl-2-100 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody (PE)
BCL2 Reactivity: Human ICFC Host: Mouse Monoclonal Bcl-2-100 PE

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
KD Validated BCL2 Reactivity: Human WB, FACS, IF (p) Host: Rabbit Monoclonal 23GB675 unconjugated Recombinant Antibody

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
BCL2 Reactivity: Human WB, IHC, FACS, IF, StM, ISt Host: Mouse Monoclonal 100-D5 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
BCL2 Reactivity: Human WB, IHC, StM Host: Rabbit Monoclonal BCL2-2210R unconjugated Recombinant Antibody

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C
Target

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name

BCL-2

Gene ID

596

UniProt

P10415

Pathways

MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling