Calnexin antibody (C-Term) (DyLight 405)

Catalog No. ABIN7273047

The Goat Polyclonal anti-Calnexin antibody is suitable to detect Calnexin in samples from Human, Mouse, Rat, Dog and Monkey. It has been validated for WB, IF and IHC (fro).

Quick Overview for Calnexin antibody (C-Term) (DyLight 405) (ABIN7273047)

Target: Calnexin (CANX)

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This Calnexin antibody is conjugated to DyLight 405

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Calnexin Antibody (DyLight 405)

Binding Specificity: C-Term

Purpose: Anti-CANX, DyLight®405

Sequence: KSDAEEDGGT VSQEEEDRKP KAEEDEILNR SPRNRKPRRE

Specificity: Detects a band of 90 kDa by Western blot whole cell lysates.

Cross-Reactivity (Details): Reacts against human, rat, mouse, canine and monkey proteins.

Characteristics: Calnexin

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide within residues 550 aa to the C-terminus of human CANX produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000, IF:1:50-1:500, IHC-F:1:200-1:1,000

Restrictions: For Research Use only

Handling

Concentration: 2.5 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: CANX

Background:

Goat polyclonal to CANX (Calnexin) - endoplasmic reticulum (ER) membrane marker conjugated to DyLight® 405. CANX is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, ER-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Calnexin, CALX, CNX, FLJ26570, histocompatibility complex class I antigen binding protein p88, IP90, major histocompatibility complex class I antigen-binding protein p88, MS952, P90 antibody.

Pathways: MAPK Signaling, Thyroid Hormone Synthesis