LRPAP1 antibody

Catalog No. ABIN7383949

The Rabbit Polyclonal anti-LRPAP1 antibody (ABIN7383949) specifically detects LRPAP1 in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for LRPAP1 antibody (ABIN7383949)

Target: LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRPAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-LRPAP1 Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human LRPAP1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LRPAP1

Target: LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))

Alternative Name: LRPAP1

Background: 39 kDa receptor-associated protein,A2MRAP,A2RAP,Alpha 2 macroglobulin receptor associated protein,Alpha 2 MRAP,Alpha-2-macroglobulin receptor-associated protein,Alpha-2-MRAP,AMRP,HBP44,Lipoprotein receptor associated protein,Low density lipoprotein receptor related protein associated protein 1,Low density lipoprotein receptor-related protein-associated protein 1,Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein,Low density lipoprotein related protein associated protein 1,low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1),Lrpap1,MGC138272,MRAP,MYP23,RAP,Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.

Molecular Weight: 41 kDa

NCBI Accession: NP_002328

UniProt: P30533