HNF1B antibody

Catalog No. ABIN7384012

The Rabbit Polyclonal anti-HNF1B antibody (ABIN7384012) specifically detects HNF1B in ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HNF1B antibody (ABIN7384012)

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF1B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-HNF1B Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human HNF1B

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HNF1B

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Alternative Name: HNF1B

Background: FJHN,Hepatocyte nuclear factor 1 beta,Hepatocyte nuclear factor 1-beta,HNF 1B,HNF 2,HNF-1-beta,HNF-1B,HNF1 beta,HNF1 homeobox B,HNF1B,HNF1B,HNF1beta,HNF2,Homeoprotein LF B3,Homeoprotein LFB3,HPC11,LF B3,LFB3,MODY 5,MODY5,TCF 2,TCF 2 protein,TCF-2,TCF2,TCF2 protein,Transcription factor 2,Transcription factor 2 hepatic,Variant hepatic nuclear factor 1,Variant hepatic nuclear factor,VHNF 1,vHNF1,This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Accession: NP_000449

UniProt: P35680

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation