DNMT3A antibody

Catalog No. ABIN7384388

This Rabbit Monoclonal antibody specifically detects DNMT3A in WB. It exhibits reactivity toward Human.

Quick Overview for DNMT3A antibody (ABIN7384388)

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DNMT3A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: R03-8H4

Product Details anti-DNMT3A Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DNMT3A

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Alternative Name: Dnmt3a

Background: DNA (cytosine 5) methyltransferase 3 alpha,DNA (cytosine 5) methyltransferase 3A,DNA (cytosine-5)-methyltransferase 3A,DNA cytosine methyltransferase 3A2,DNA methyltransferase 3 alpha,DNA methyltransferase 3a,DNA methyltransferase HsaIIIA,DNA MTase HsaIIIA,DNM3A,DNMT 3a,DNMT,Dnmt3a,DNMT3A2,M.HsaIIIA,MCMT,OTTHUMP00000201149,TBRS,CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight:

Observed_MW: 130kDa

Calculated_MW: 102kDa

Gene ID: 1788

UniProt: Q9Y6K1