PCBP2 antibody
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- Target See all PCBP2 Antibodies
- PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This PCBP2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity Purified
- Clone
- R01-2F5
- Isotype
- IgG
- Top Product
- Discover our top product PCBP2 Primary Antibody
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- Application Notes
- WB 1:500-1:1000
- Restrictions
- For Research Use only
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- Concentration
- 300 μg/mL
- Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
- Alternative Name
- PCBP2 (PCBP2 Products)
- Synonyms
- HNRNPE2 antibody, HNRPE2 antibody, hnRNP-E2 antibody, AW412548 antibody, Hnrpx antibody, alphaCP-2 antibody, PCBP3 antibody, fb36h02 antibody, wu:fb36h02 antibody, zgc:55964 antibody, PCBP2 antibody, poly(rC) binding protein 2 antibody, poly(rC) binding protein 2 L homeolog antibody, PCBP2 antibody, Pcbp2 antibody, pcbp2 antibody, pcbp2.L antibody
- Background
- PCBP2,HNRNPE2,HNRPE2,hnRNP-E2,The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
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Observed_MW: 35/45kDa
Calculated_MW: 39kDa
- Gene ID
- 5094
- UniProt
- Q15366
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