Caspase 1 antibody

Catalog No. ABIN7384556

This Rabbit Polyclonal antibody specifically detects Caspase 1 in WB. It exhibits reactivity toward Zebrafish (Danio rerio).

Quick Overview for Caspase 1 antibody (ABIN7384556)

Target: Caspase 1 (CASP1)

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Caspase 1 Antibody

Purification: Antigen Affinity Purification

Immunogen: Synthetic peptide corresponding to Zebrafish caspase-1 conjugated to keyhole limpet haemocyanin.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-2000, IP: 3 μg/sample, IF: 1:100-200

Restrictions: For Research Use only

Handling

Concentration: 5 mg/mL

Buffer: PBS with 0.1 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Caspase 1

Target: Caspase 1 (CASP1)

Alternative Name: Caspase-1

Background: CASP1,ICE,IL1BC,P45,caspase-1,Caspase 1,CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor

Molecular Weight:

Observed_MW: 20kDa,42kDa

Calculated_MW: 45, 42, 35, 22, 20kDa

Gene ID: 57933

UniProt: Q9I9L7

Pathways: Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome