MYBL2 antibody (AA 450-500)
Quick Overview for MYBL2 antibody (AA 450-500) (ABIN7448426)
Target
See all MYBL2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 450-500
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Purpose
- Rabbit anti-B-Myb IHC Antibody, Affinity Purified
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Predicted Reactivity
- Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Crab-eating macaque,Ferret,Small-eared galago,Northern white-cheeked gibbon,White-tufted-ear marmoset,Thirteen-lined ground squirrel
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Purification
- Affinity Purified
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Immunogen
- Between AA 450 and 500
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Isotype
- IgG
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Application Notes
- 1:100 - 1:500
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Restrictions
- For Research Use only
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Concentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))
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Alternative Name
- B-Myb
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Background
- Background: B-myb is transcription factor involved in multiple cellular processes such as cell survival, proliferation, and differentiation. B-myb was identified in a low-stringency screen of a T-cell cDNA library probed with a C-myb probe. C-myb is a cellular proto-oncogene highly conserved in vertebrates and invertebrates. The chicken c-myb proto-oncogene was the first ortholog discovered. Investigation of the origins of the avian myeloblastosis virus (AMV) led to the discovery that the AMV genome contained transduced sequences from normal chicken cellular DNA that resulted in a viral oncogenic version (v-myb) of the c-myb gene. B-myb is cell cycle regulated and expressed in all proliferating cells. Recent studies show that it is the only myb family member detected in embryonic stem cells and is essential to cell cycle progression and genomic stability.
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Gene ID
- 4605
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NCBI Accession
- NP_002457
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UniProt
- P10244
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Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding
Target
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