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CHEK2 antibody (AA 475-525)

The Rabbit Polyclonal anti-CHEK2 antibody has been validated for IHC. It is suitable to detect CHEK2 in samples from Human.

Catalog No. ABIN7448477

Datasheet as PDF

Quick Overview for CHEK2 antibody (AA 475-525) (ABIN7448477)

Target

See all CHEK2 Antibodies

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Reactivity

Human

Host

Rabbit

Clonality

Polyclonal

Conjugate

This CHEK2 antibody is un-conjugated

Application

Immunohistochemistry (IHC)

Discover our top product CHEK2 Primary Antibody

Binding Specificity
26

25

19

17

16

16

15

15

9

8

8

8

6

5

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 475-525

Purpose

Rabbit anti-Chk2 IHC Antibody, Affinity Purified

Predicted Reactivity

Orangutan,Chimpanzee

Purification

Affinity Purified

Immunogen

Between AA 475 and 525

Isotype

IgG
anti-Checkpoint Kinase 2 (CHEK2) (pThr387) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 111-141), (N-Term) antibody
CHEK2 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB19067 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 4B7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reactivity: Human, Dog WB, IHC, IP, IHC (p), FACS Host: Mouse Monoclonal 2H5 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reactivity: Human, Dog WB, IHC, IF, IP, IHC (p), FACS Host: Mouse Monoclonal 5C4 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reactivity: Human, Monkey, Dog WB, IHC, IF, IHC (p), FACS Host: Mouse Monoclonal 10G7 unconjugated

Application Notes

1:100 - 1:500

Restrictions

For Research Use only
Concentration

500 μg/mL

Buffer

Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Expiry Date

12 months
Target

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Alternative Name

Chk2

Background

Background: Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are RAD53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, Brca1, Cdc25A and Cdc25C to cause cell cycle arrest. Chk2 is also known as serine/threonine-protein kinase CHK2, CHEK2, CDS1, LFS2, RAD53, HuCds1, and PP1425.

Gene ID

11200

NCBI Accession

NP_009125

UniProt

O96017

Pathways

p53 Signaling, Apoptosis, Cell Division Cycle