CPSF2 antibody (AA 450-500)

Catalog No. ABIN7448485

This Rabbit Polyclonal antibody specifically detects CPSF2 in IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for CPSF2 antibody (AA 450-500) (ABIN7448485)

Target: CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CPSF2 Antibody

Binding Specificity: AA 450-500

Purpose: Rabbit anti-CPSF100 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,X. tropicalis,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Panda,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Thirteen-lined ground squirrel,African elephant,Crab-eating macaque,Little brown bat,Small-eared galago,Gray short-tailed opossum,Zebra finch,Tasmanian devil,Green anole,Naked mole rat

Purification: Affinity Purified

Immunogen: Between AA 450 and 500

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CPSF2

Target: CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Alternative Name: CPSF100

Background: Background: CPSF100/CPSF2 (cleavage and polyadenylation specific factor 2, 100 kDa subunit) is a subunit of the cleavage and polyadenylation specificity factor (CPSF) involved in mammalian mRNA 3'-end processing. CPSF, along with CstF (cleavage and stimulation factor), is critical for the recognition of cis-acting sequence elements on the pre-mRNA that dictate the site of cleavage and subsequent polyadenylation. CPSF exists as a complex of four proteins that includes CPSF160/CPSF1, CPSF100/CPSF2, CPSF73/CPSF3, and CPSF30/CPSF4. CPSF100/CPSF2 and CPSF73/CPSF3 are both members of the metallo-beta-lactamase superfamily of zinc-dependent hydrolases.

Gene ID: 53981

NCBI Accession: NP_059133

UniProt: Q9P2I0