COPS5 antibody (AA 175-225)

Catalog No. ABIN7448494

This Rabbit Polyclonal antibody specifically detects COPS5 in IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for COPS5 antibody (AA 175-225) (ABIN7448494)

Target: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS5 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-COPS5 Antibody

Binding Specificity: AA 175-225

Purpose: Rabbit anti-CSN5 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Zebrafish,X. laevis,X. tropicalis,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Chimpanzee,Medaka fish,Atlantic salmon,Rainbow trout,Tasmanian devil,Nile tilapia,White-tufted-ear marmoset,Crab-eating macaque,Duckbill platypus,Pipidae,West Indian ocean coelacanth,Green anole,Gray short-tailed opossum,Japanese pufferfish,Small-eared galago,African elephant,Chinese hamster,European seabass,Naked mole rat,Thirteen-lined ground squirrel,Rainbow smelt,Little brown bat,Giant tiger prawn,Three-spined stickleback,Northern white-cheeked gibbon,Starlet sea anemone,Spotted green pufferfish,Zebra finch

Purification: Affinity Purified

Immunogen: Between AA 175 and 225

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for COPS5

Target: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Alternative Name: CSN5

Background: Background: CSN5 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals its function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. CSN also possesses kinase activity. CSN5 has been identified as the subunit that functions to remove Nedd8, an ubiquitin-like modifier, from cullin-based E3-ubiquitin ligases. CSN5 also functions as a coactivator of nuclear receptors. COP9 signalsome complex subunit 5, signalsome subunit 5, SGN5, jun activation domain-protein 1, COPS5, JAB1, MOV-34, MGC3149.

Gene ID: 10987

NCBI Accession: NP_006828

UniProt: Q92905

Pathways: Cell Division Cycle