Cyclin E1 antibody (AA 360-410)

Catalog No. ABIN7448507

The Rabbit Polyclonal anti-Cyclin E1 antibody has been validated for IHC. It is suitable to detect Cyclin E1 in samples from Human.

Quick Overview for Cyclin E1 antibody (AA 360-410) (ABIN7448507)

Target: Cyclin E1 (CCNE1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin E1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Cyclin E1 Antibody

Binding Specificity: AA 360-410

Purpose: Rabbit anti-Cyclin E1 IHC Antibody, Affinity Purified

Predicted Reactivity: Orangutan,Gorilla,Chimpanzee

Purification: Affinity Purified

Immunogen: Between AA 360 and 410

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Cyclin E1

Target: Cyclin E1 (CCNE1)

Alternative Name: Cyclin E1

Background: Background: Cyclin E1 is a regulatory subunit of the CDK2 kinase. Cyclin E is central for the regulation of the G1/S transition and its abundance is tightly regulated throughout the cell cycle via ubiquitination. Cyclin E has been the subject of intense study in relation to tumorigenesis and cancer management and prognosis.

Gene ID: 898

NCBI Accession: NP_001229

UniProt: P24864

Pathways: Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases