GIT2 antibody (AA 500-550)

Catalog No. ABIN7448581

This Rabbit Polyclonal antibody specifically detects GIT2 in IHC. It exhibits reactivity toward Human.

Quick Overview for GIT2 antibody (AA 500-550) (ABIN7448581)

Target: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIT2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-GIT2 Antibody

Binding Specificity: AA 500-550

Purpose: Rabbit anti-GIT2 IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,X. laevis,X. tropicalis,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Small-eared galago,Little brown bat,Zebra finch,Thirteen-lined ground squirrel,Naked mole rat,African elephant,Crab-eating macaque,Tasmanian devil,West Indian ocean coelacanth,Chinese hamster,White-tufted-ear marmoset,Northern white-cheeked gibbon,Chinese softshell turtle

Purification: Affinity Purified

Immunogen: Between AA 500 and 550

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for GIT2

Target: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Alternative Name: GIT2

Background: Background: G-protein-coupled receptor kinase interactor 1 (GIT1) and G-protein-coupled receptor kinase interactor 2 (GIT2) are GTPase-activating proteins for ADP-ribosylation (Arf) GTPases. GIT1 and GIT2 regulate Arf activity and the sequestration of activated G protein-coupled receptors from the surface of the cell. These activities have effects on multiple cellular processes such as cell migration, T-cell activation, and centrosome dynamics. Both GIT proteins also serve as scaffolds to link signaling molecules.

Gene ID: 9815

NCBI Accession: NP_476510

UniProt: Q14161

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling