KDM5A antibody (AA 1640-1690)

Catalog No. ABIN7448612

The Rabbit Polyclonal anti-KDM5A antibody is suitable to detect KDM5A in samples from Human. It has been validated for IHC.

Quick Overview for KDM5A antibody (AA 1640-1690) (ABIN7448612)

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM5A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-KDM5A Antibody

Binding Specificity: AA 1640-1690

Purpose: Rabbit anti-JARID1A/RBP2 IHC Antibody, affinity purified

Predicted Reactivity: Mouse,Rat,Dog,Horse,Rabbit,Guinea pig_10141,Panda,Orangutan,Gorilla,Northern white-cheeked gibbon,Small-eared galago,Chinese hamster

Purification: Affinity Purified

Immunogen: Between AA 1640 and 1690

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for KDM5A

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Alternative Name: JARID1A/RBP2

Background: Background: JARID1A/RBP2 is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JARID1A/RBP2 functions to specifically demethylate lys-4 of histone 3 and interacts with the tumor suppressor protein pRb.

Gene ID: 5927

NCBI Accession: NP_005047

UniProt: P29375

Pathways: Chromatin Binding, Warburg Effect