KDM3B antibody (C-Term)

Catalog No. ABIN7448615

The Rabbit Polyclonal anti-KDM3B antibody has been validated for IHC. It is suitable to detect KDM3B in samples from Human.

Quick Overview for KDM3B antibody (C-Term) (ABIN7448615)

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM3B antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-KDM3B Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-JMJD1B IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,Duckbill platypus,Small-eared galago,Little brown bat,Gray short-tailed opossum,Green anole,Northern white-cheeked gibbon,Tasmanian devil,West Indian ocean coelacanth,Naked mole rat,Zebra finch,African elephant

Purification: Affinity Purified

Immunogen: Between AA 1710 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for KDM3B

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Alternative Name: JMJD1B

Background: Background: JMJD1B is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD1B was identified as the 5qNCA gene that lies within a locus on chromosome 5 that is frequently deleted in myeloid leukemias and myelodysplasias. JMJD1B has been demonstrated to have growth suppressive activity and is implicated as a tumor suppressor gene.

Gene ID: 51780

NCBI Accession: NP_057688

UniProt: Q7LBC6

Pathways: Warburg Effect