MAD2 antibody (AA 100-150)

Catalog No. ABIN7448633

The Rabbit Polyclonal anti-MAD2 antibody is suitable to detect MAD2 in samples from Human. It has been validated for IHC.

Quick Overview for MAD2 antibody (AA 100-150) (ABIN7448633)

Target: MAD2

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAD2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-MAD2 Antibody

Binding Specificity: AA 100-150

Purpose: Rabbit anti-MAD2 IHC Antibody, Affinity Purified

Predicted Reactivity: Bovine,Guinea pig_10141,Pig,Orangutan,Monkey,Gorilla,Chimpanzee,Ferret,Olive baboon,White-tufted-ear marmoset,Thirteen-lined ground squirrel,Northern white-cheeked gibbon,Small-eared galago,Crab-eating macaque,Naked mole rat

Purification: Affinity Purified

Immunogen: Between AA 100 and 150

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MAD2

Target: MAD2

Background: Background: MAD2 (Mitotic Arrest Deficiency 2) is a component of the mitotic spindle-assembly checkpoint that ensures that all chromosomes are aligned at the metaphase plate before the onset of anaphase. MAD2 is a subunit of the MCC complex that includes BubR1, Bub3, Cdc20 and Mad2, which may function to inhibit the APC/c (Anaphase Promoting Complex/Cyclosome). MAD2 is regulated by MAD1.

Gene ID: 4085

NCBI Accession: NP_002349

UniProt: Q13257