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MAML1 antibody (AA 75-125)

MAML1 Reactivity: Human IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7448636
  • Target See all MAML1 Antibodies
    MAML1 (Mastermind-Like 1 (MAML1))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 75-125
    Reactivity
    • 30
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 1
    • 1
    Rabbit
    Clonality
    • 31
    Polyclonal
    Conjugate
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    This MAML1 antibody is un-conjugated
    Application
    • 26
    • 21
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Purpose
    Rabbit anti-MAML1 IHC Antibody, Affinity Purified
    Predicted Reactivity
    Chimpanzee
    Purification
    Affinity Purified
    Immunogen
    Between AA 75 and 125
    Isotype
    IgG
    Top Product
    Discover our top product MAML1 Primary Antibody
  • Application Notes
    1:100 - 1:500
    Restrictions
    For Research Use only
  • Concentration
    250 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Expiry Date
    12 months
  • Target
    MAML1 (Mastermind-Like 1 (MAML1))
    Alternative Name
    MAML1 (MAML1 Products)
    Synonyms
    mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody
    Background
    Background: There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML1 is a critical coactivator for NOTCH signaling. MAML1 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML1 has been observed to interact with p300 to acetylate histones H3 and H4. MAML1 also interacts with p53 and functions independent of NOTCH signaling, as a coactivator of p53 target genes.
    Gene ID
    9794
    NCBI Accession
    NP_055572
    UniProt
    Q92585
    Pathways
    Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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