MSH6 antibody (AA 350-400)

Catalog No. ABIN7448674

This Goat Polyclonal antibody specifically detects MSH6 in IHC. It exhibits reactivity toward Human.

Quick Overview for MSH6 antibody (AA 350-400) (ABIN7448674)

Target: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This MSH6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-MSH6 Antibody

Binding Specificity: AA 350-400

Purpose: Goat anti-MSH6 IHC Antibody, Affinity Purified

Predicted Reactivity: Orangutan,Gorilla,Chimpanzee,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 350 and 400

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 500 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MSH6

Target: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Alternative Name: MSH6

Background: Background: MSH6 is a component of the DNA mismatch repair (MMR) system that functions to recognize base-base mismatches and framshift mispairs. MSH6 forms a heterodimer with MSH2 and is also part of the BRCA1-associated genome surveillance complex (BASC). Mutations in MSH6 have been linked to endometrial carcinoma.

Gene ID: 2956

NCBI Accession: NP_000170

UniProt: P52701

Pathways: DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response