p300 antibody (AA 950-1000)

Catalog No. ABIN7448706

The Rabbit Polyclonal anti-p300 antibody (ABIN7448706) specifically detects p300 in IHC. The antibody is reactive with Human samples.

Quick Overview for p300 antibody (AA 950-1000) (ABIN7448706)

Target: p300 (EP300) (E1A Binding Protein P300 (EP300))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This p300 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-p300 Antibody

Binding Specificity: AA 950-1000

Purpose: Rabbit anti-p300 IHC Antibody, Affinity Purified

Predicted Reactivity: Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque

Purification: Affinity Purified

Immunogen: Between AA 950 and 1000

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for p300

Target: p300 (EP300) (E1A Binding Protein P300 (EP300))

Alternative Name: p300

Background: Background: By sequence similarity p300 is related to CBP (CREB-binding protein) and functions as a histone acetyltransferase that can regulate transcription by influencing chromatin organization. P300 has been demonstrated to bind to phosphorylated CREB to mediate cAMP-gene regulation. P300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha).

Gene ID: 2033

NCBI Accession: NP_001420

UniProt: Q09472

Pathways: p53 Signaling, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size