PDZ-RhoGEF (AA 1472-1522) antibody
The Rabbit Polyclonal anti-PDZ-RhoGEF antibody (ABIN7448721) specifically detects PDZ-RhoGEF in IHC.
The antibody is reactive with Human samples.
Catalog No. ABIN7448721
$532.77
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Quick Overview for PDZ-RhoGEF (AA 1472-1522) antibody (ABIN7448721)
Target
PDZ-RhoGEF
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Un-conjugated
Application
Immunohistochemistry (IHC)
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Binding Specificity
- AA 1472-1522
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Purpose
- Rabbit anti-PDZ-RhoGEF IHC Antibody, Affinity Purified
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Predicted Reactivity
- Gorilla,Chimpanzee
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Purification
- Affinity Purified
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Immunogen
- Between AA 1472 and 1522
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Isotype
- IgG
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anti-PDZ-RhoGEF (N-Term) antibody
Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
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Application Notes
- 1:100 - 1:500
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Restrictions
- For Research Use only
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Concentration
- 100 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- PDZ-RhoGEF
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Background
- Background: PDZ-RhoGEF. (PDZ domain-containing Rho guanine nucleotide exchange factor) catalyzes the exchange of GDP for GTP on the GTPase, Rho, to activate downstream signaling pathways. It contains a PDZ [post synaptic density protein (PSD95), Drosophila dis large tumor suppressor (DIgA), and zonula occludens-1 protein (zo-1)] domain which is an 80-90 amino acid structural domain found in signaling proteins in bacteria, yeast, plants, and animals. PDZ-RhoGEF has been shown to be important to cell migration and the regulation of adhesion movement and trailing edge retraction.
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Gene ID
- 9826
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NCBI Accession
- NP_055599
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UniProt
- O15085
Target
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